Research Associate, Tissue Culture & Molecular Biology

Full Time

Brooklyn, New York, United States

Job description

Scismic is supporting the growth of a therapeutics biotech company in Brooklyn, NY. We are in search of a Research Associate - Molecular Biology who will help us harness the power of RNAi to create powerful and novel RNA therapeutics.

We are seeking highly motivated individuals to work with our model creation team to expand its capacity of Genetic Engineering Services. A suitable candidate should be an effective communicator, planning, prioritizing, and executing projects to meet commitments with a detail orientated mindset.
 Job Responsibilities:
  • The job position will primarily work with the cell culture team on the validation and ES cell targeting process of our RNAi and CRISPR/Cas9 lines, as well as genotyping.  They will also assist our Director of Embryology and cell culture/animal technician team with organization, timelines, and compiling data reports. 
  • In addition, the role will require working with specific projects or aspects imperative to our operational pipeline, working with the Genetic Engineering team on the targeting vector cloning, DNA sequence analysis, and vital upstream preparation for our validation and ES cell targeting team members.  Projects will be based on our RNAi and CRISPR/Cas9 pipelines. Genotyping experience is a plus. The candidate will also assist our Director of Genetic Engineering Services and other molecular cloning team members with organization, timelines, and compiling data reports. 
  • Candidate will also have basic lab duties to prepare laboratory equipment, instruments, solutions, stains, assays and other supplies.
Successful candidates will be part of an innovative and creative team with the opportunity to apply their creativity to the company's core vision.
Minimum Education and Experience Needed: 
  • BS in Biology, Molecular Biology, Genetics, Biotechnology, or related field
  • Minimum 1 to 2 years of relevant research lab or industry experience 
  • Must properly follow protocols, procedures, and instruction, attention to detail, work in a fast pace environment to meet deadlines, be eager to learn, and be able to work in a team and independently.
  • Has good record keeping skills
  • Has minimum 1-year experience with cell culture of mammalian cell lines.
  • Has knowledge to perform transfections of various cell lines. 
  • Has experience handling ES cells, including analyzing and quantitating data from experiments is highly desired. 
  • Routinely performed molecular biology techniques such as genomic DNA extraction, PCR, plasmid mini-prep, and DNA sequence analysis.
  • Has good knowledge of scientific principles, methods and processes (technical and/or theoretical) used to conduct systematic and objective inquiry, methods of data collection and analyses, and interpreting and reporting results are required, as well as the ability to operate instruments and equipment and proficiency in related information technology including Microsoft Office, VectorNTI, SnapGene etc. 
  • Has a working knowledge of RNA interference, shRNA and/or siRNA, as well as gene editing techniques including homologous recombination and CRISPR/Cas9, and their applications to study gene function. 
  • Can effectively summarize and clearly report on a wide range of service line related tasks
  • Must be able to operate lab instruments; must be familiar with MS Excel and computers. 
  • Has excellent written and oral communication skills. 
  • Can interact with all individuals in productive ways to enhance the company's goals and core vision. 
  • Shows respect and maintains a professional attitude to all lab members and outside collaborators. 

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