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(Senior) Scientist - Protein Engineering / Assay Development
Full Time
Boston, Massachusetts, United States
Job description
Scismic is supporting the growth of a well-funded, VC-backed biotech startup with a mission to invent next-generation technologies to design drugs that will improve and save patient lives.
We are seeking a Scientist to join our team! This is a key role in the pursuit of innovations that further expand the scale and capability of company's technology. You will apply high-throughput protein engineering and molecular biology principles to advance our technology. Responsibilities include the design, construction, and high-throughput screening of complex protein libraries. You’ll collaborate with a multidisciplinary team of creative scientists to support the deployment of M-codes for in vivo multiplexed applications. As a key member of our rapidly growing team, you will help build and foster a culture that embraces scientific excellence and diversity of ideas.
We are seeking a Scientist to join our team! This is a key role in the pursuit of innovations that further expand the scale and capability of company's technology. You will apply high-throughput protein engineering and molecular biology principles to advance our technology. Responsibilities include the design, construction, and high-throughput screening of complex protein libraries. You’ll collaborate with a multidisciplinary team of creative scientists to support the deployment of M-codes for in vivo multiplexed applications. As a key member of our rapidly growing team, you will help build and foster a culture that embraces scientific excellence and diversity of ideas.
What You’ll Do
- Advance the scale, sensitivity and robustness of our M-Code multiplexing technology by combining protein engineering, synthetic library, directed evolution and in vitro display approaches.
- Prioritize problems and improvements and formulate strategies to solve them.
- Work both independently and in collaboration with experimental, computational, and hybrid biologists to design, execute, analyze and interpret experiments.
- Mentor junior scientists in developing skills essential to the execution of rigorous scientific research
- Ensure data generated is documented in a timely and organized fashion, and present ideas and results to
colleagues and leadership - Coordinate and build efficient working relationships with the Protein Sciences and In Vivo Biology teams to support the deployment of M-Codes technologies for screening drug candidates in animal models.
Who You Are
You love to tinker with biological parts and enjoy the challenge of troubleshooting en route to the development of a novel assay. You are passionate about combining both rational design and unbiased approaches in problem solving.
Requirements:
- A proven track record executing high-throughput screens and/or protein/enzyme engineering work.
- Strong technical proficiency in key biochemistry/molecular biology techniques, including: cloning, protein purification and ELISA/Western analysis.
- Hands-on experience in NGS library preparation.
- Strong desire to work collaboratively within a fast-paced and multidisciplinary team environment.
- Detail-oriented with excellent organizational and communication skills.
- Interest and/or some experience mentoring junior scientists.
- Self-motivated and scientifically curious
- M.S + at least 5 years of industry experience in Biochemistry, Bioengineering, Molecular Biology or related field OR
- PhD experience in Biochemistry, Bioengineering, Molecular Biology or related field
Nice to Haves:
- 1-3 years Startup/Biotech/Pharma experience in protein engineering or assay development.
- Experience in either directed evolution or phage/yeast/mammalian or related display technologies.
- Experience collaborating with computational scientists.
- Experience working with antibody or antibody-like molecules.
We value different experiences and different ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.